ImmuSmol代表“針對(duì)小分子的免疫球蛋白[抗體]”。雖然傳統(tǒng)抗體僅識(shí)別蛋白質(zhì)等大分子，但I(xiàn)mmuSmol設(shè)計(jì)并開發(fā)出能夠靶向低分子量實(shí)體（<900 Da）的抗體。
因此，氨基酸，脂質(zhì)，糖類，毒素，藥物......實(shí)際上任何小分子都可以以高親和力和特異性來解決。小分子抗體與現(xiàn)有的基于抗體的技術(shù)*兼容，為研究，診斷和治療開辟了全新的可能性。
參考：IS001
種也是僅有的一種可供研究使用的抗-3-羥基環(huán)氧乙酸抗體。5B2-G2原代小鼠單克隆抗體在人腫瘤和腦組織中均經(jīng)過IHC驗(yàn)證。當(dāng)通過競(jìng)爭(zhēng)性ELISA測(cè)試時(shí)，抗體顯示出強(qiáng)親和力和高特異性。
克隆 | 單克隆抗體（克隆5B2-G2） |
主辦 | 老鼠 |
有條件的申請(qǐng) | IHC |
物種反應(yīng)性 | 與所有物種發(fā)生反應(yīng) |
格式 | 50μL |
IHC染色顯示3-羥基0氨基苯甲酸在人結(jié)腸癌細(xì)胞以及來自腫瘤微環(huán)境的細(xì)胞中的積累。將人石蠟包埋的結(jié)腸腫瘤組織進(jìn)行pH = 6的抗原修復(fù)，并與初級(jí)3-羥基 - 0氨基苯甲酸抗體（1/1000稀釋）一起溫育過夜。在聚合物綴合的二抗暴露后，通過DAB著色觀察到染色。
產(chǎn)品概述
產(chǎn)品名稱 | 3-羥基0氨基苯甲酸抗體 |
同義詞 | 抗3-羥基 - 0氨基苯甲酸抗體 2-氨基-3-羥基苯甲酸抗體 3-OH-0氨基苯甲酸抗體 3-羥基蒽醌抗體 3-OHAA抗體 |
免疫原 | 共軛的3-羥基0氨基苯甲酸 |
同型 | IgG1 k鏈 |
克隆 | 克隆5B2-G2 |
特異性 | 當(dāng)在競(jìng)爭(zhēng)性ELISA中測(cè)試時(shí)，抗-3-羥基 - 對(duì)氨基苯甲酸抗體與0氨基苯甲酸或Cinnabarinic酸結(jié)合物沒有顯示出任何顯著的交叉反應(yīng)性。 |
批號(hào) | 140201 |
存儲(chǔ)
形成 | 液體 |
純度 | 純化的IgG |
濃度 | 0.5mg / ml |
存儲(chǔ) | 儲(chǔ)存在4°C |
存儲(chǔ)緩沖區(qū) | 儲(chǔ)存在+ 4°C短期（1-2周）。分裝并在-20°C下長期保存。避免反復(fù)凍/融循環(huán) |
協(xié)議
免疫組化（IHC） | 以1：200-1：2000稀釋。 在石蠟包埋和冷凍切片上開始IHC染色方案之前，進(jìn)行熱抗原修復(fù)（pH = 6） |
免疫熒光（IF） | 在石蠟包埋和冷凍切片上以1：100-1：1000稀釋。進(jìn)行熱抗原修復(fù)并與熒光染料綴合的二抗孵育 |
注釋 | 宜工作稀釋度必須由終用戶確定 |
限制 | 僅供研究使用 |
貨號(hào) | 品名 | 規(guī)格 | 品牌 |
IS001 | 3-HydroxyAnthranilic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS002 | Quinolinic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS003 | L-Kynurenine mouse monoclonal Antibody | 50µL | immusmol |
IS004 | Quinaldic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS005 | Cinnabarinic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS009 | Xanthurenic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS010 | Kynurenic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS011 | L-Tryptophan mouse monoclonal Antibody | 50µL | immusmol |
IS013 | Anthranilic Acid mouse monoclonal Antibody | 50µL | immusmol |
IS018 | L-Glutamate mouse monoclonal Antibody | 50µL | immusmol |
IS040 | Serotonin monoclonal Antibody | 50µL | immusmol |
IS1001 | L-Glutamate Rabbit polyclonal Antibody | 50µL | immusmol |
IS1002 | D-Glutamate polyclonal Antibody | 50µL | immusmol |
IS1003 | L-Serine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1004 | D-Serine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1005 | Dopamine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1006 | GABA Rabbit polyclonal Antibody | 50µL | immusmol |
IS1007 | Serotonin Rabbit polyclonal Antibody | 50µL | immusmol |
IS1010 | Quinolinic Acid Rabbit polyclonal Antibody | 50µL | immusmol |
IS1011 | Kynurenic Acid Rabbit polyclonal Antibody | 50µL | immusmol |
IS1012 | L-Kynurenine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1019 | 3MethoxyTyramine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1028 | Normetanephrine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1030 | L-DOPA Rabbit Polyclonal Antibody | 50µL | immusmol |
IS1033 | Octopamine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1034 | Glycine Rabbit polyclonal Antibody | 50µL | immusmol |
IS1035 | Serotonin Goat polyclonal Antibody | 50µL | immusmol |
IS1036 | GABA Chicken polyclonal Antibody | 50µL | immusmol |
IS1042 | Noradrenaline Rabbit Polyclonal Antibody | 50µL | immusmol |
SP-A-1000 | STAINperfect Immunostaining Kit A | 1kit | immusmol |
SP-T-001 | STAINperfect Immunostaining Kit A - Trial pack* | 1 kit + 2 Abs | immusmol |
ISE-2227 | Kynurenine/Tryptophan ratio ELISA pack | 1pack | immusmol |
BA-E-2200 | L-Kynurenine ELISA kit Any sample | 1kit | immusmol |
BA-E-5600 | 3 Catecholamines ELISA kit Any sample | 1kit | immusmol |
BA-E-6600 | 3 Catecholamines ELISA kit Plasma & Urine samples | 1kit | immusmol |
BA-E-1900 | 5-HIAA ELISA kit Urine samples | 1kit | immusmol |
BA-E-5300 | Dopamine ELISA kit Any sample | 1kit | immusmol |
BA-E-6300 | Dopamine ELISA kit Urine & Plasma samples | 1kit | immusmol |
BA-E-5400 | Epinephrine - Norepinephrine ELISA kit - Any sample | 1kit | immusmol |
BA-E-6500 | Epinephrine - Norepinephrine ELISA kit - Plasma & Urine | 1kit | immusmol |
BA-E-5100 | Epinephrine ELISA kit Any sample | 1kit | immusmol |
BA-E-6100 | Epinephrine ELISA kit Urine & Plasma samples | 1kit | immusmol |
BA-E-8300 | Free Metanephrine - Normetanephrine ELISA kit - Plasma samples | 1kit | immusmol |
BA-E-2500 | GABA ELISA kit Any sample | 1kit | immusmol |
BA-E-2400 | Glutamate ELISA kit Any sample | 1kit | immusmol |
BA-E-2100 | Glycine ELISA kit Urine samples | 1kit | immusmol |
BA-E-5800 | Histamine ELISA kit Any sample | 1kit | immusmol |
BA-E-1000 | Histamine ELISA kit Urine & Plasma samples | 1kit | immusmol |
BA-E-1700 | Histamine ELISA kit Urine, Cell culture, Whole blood | 1kit | immusmol |
BA-E-1100 | Histamine release kit Whole blood samples | 1kit | immusmol |
BA-E-2700 | L-Tryptophan ELISA kit Any sample | 1kit | immusmol |
BA-E-8100 | Metanephrine ELISA kit Plasma samples | 1kit | immusmol |
BA-E-8400 | Metanephrine ELISA kit Urine samples | 1kit | immusmol |
BA-E-8600 | Metanephrine-Normetanephrine ELISA kit - Urine samples | 1kit | immusmol |
BA-E-5200 | Norepinephrine ELISA kit Any sample | 1kit | immusmol |
BA-E-6200 | Norepinephrine ELISA kit Urine & Plasma samples | 1kit | immusmol |
BA-E-5500 | Norepinephrine-Dopamine ELISA Any sample | 1kit | immusmol |
BA-E-8200 | Normetanephrine ELISA kit Plasma samples | 1kit | immusmol |
BA-E-8500 | Normetanephrine ELISA kit Urine samples | 1kit | immusmol |
BA-E-5900 | Serotonin ELISA kit Any sample | 1kit | immusmol |
BA-E-8900 | Serotonin ELISA kit Serum, Urine, Platelets | 1kit | immusmol |
